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Capacity Building Program to Develop a Wastewater-Based Epidemiology Framework for COVID-19 : Case Studies from Ecuador and Uruguay (英语)

The purpose of this global technical guidance note is to share best practices on how to build capacity to establish wastewater-based epidemiology (WBE) in low- and middle-income countries (LMICs) for Coronavirus disease 2019 (COVID-19) monitoring. It includes lessons learned on knowledge transfer for sample collection, laboratory analysis, partnership creation, and stakeholder engagement to strengthen existing epidemic preparedness and response systems. WBE can be applied to different types of wastewater samples (for example, wastewater influent, sludge) and to different targets (for example, biological pathogens, pharmaceuticals and illicit drugs, environmental contaminants). This global technical guidance note focuses on lessons learned from two capacity building projects conducted in Ecuador and Uruguay in 2020-2021 that used wastewater influent to measure severe acute respiratory syndrome (SARS) - CoV-2, the virus that causes COVID-19.